| Bartolomeu Perestrello | |
| B: | 1447 |
| Porto Santo, Funchal, Portugal | |
| D: | Yes, date unknown |
| Violante Moniz Perestrello | |
| B: | 1450 |
| Porto Santo, Funchal, Portugal | |
| D: | Yes, date unknown |
| Diego Colon | |
| B: | Abt 1480 |
| Lisbon, Lisbon, Portugal | |
| D: | Between 25 Jan 1576 and 1577 |
| Pueblo DE Montalban, Toledo, Spain | |
| Maria De Toledo | |
| B: | 1484 |
| Alba, Spain | |
| M: | 1508 |
| Madrid, Madrid, Spain | |
| D: | Yes, date unknown |
| Felipa Perestrello | |
| B: | 1455 |
| Porto Santo, Funchal, Portugal | |
| D: | 1484 |
| Lisbon, Lisbon, Portugal | |
| Cristobal Colon | |
| B: | 25 Aug 1448 |
| Cuba, Beja, Portugal | |
| M: | 1478 |
| Lisbon, Lisbon, Portugal | |
| D: | 20 May 1506 |
| Valladoid, Valladoid, Spain | |
| Isabel Perestrello | |
| B: | 1456 |
| Porto Santo, Funchal, Portugal | |
| D: | Yes, date unknown |
| Catarina Perestrello | |
| B: | 1458 |
| Porto Santo, Funchal, Portugal | |
| D: | Yes, date unknown |
| Isabel Moniz | |
| B: | 1429 |
| Porto Santo, Funchal, Portugal | |
| D: | Yes, date unknown |
| Bartolomeu Barretto Perestrello | |
| B: | 1396 |
| Lisbon, Lisbon, Portugal | |
| M: | 1446 |
| Porto Santo, Funchal, Portugal | |
| D: | 1458 |
| Baleira, Porto Santo, Funchal, Portugal | |
|
| Vasco Martins Moniz | |
| B: | 1415 |
| Algarve (Now Faro), Portugal | |
| D: | 1510 |
| Torrao, Portugal | |
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