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 | Isaac Seldon Alfred McSpadden (1804-1853) |
| Thomas Seldon 'Seth' McSpadden (1828- )  |
 | Margaret McSpadden (1829-1891) |
| George Marshall McSpadden (1834-1910) |
| James Taylor McSpadden (1836- ) |
| Eliza A. McSpadden (1839-1868) |
| Amanda Lucinda McSpadden (1840- ) |
| Emily Dozier McSpadden (1842- ) |
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