| Children |
| | 1. Solomon Despain, b. Abt 1783, Green County, Kentucky  d. Bef 20 May 1841, Green County, Kentucky (Age 58 years) |
| | 2. James Despain, b. Abt 1785 d. Yes, date unknown |
| | 3. William Despain, b. 1788 d. 4 Jul 1844, Green County, Kentucky (Age 56 years) |
| | 4. Joseph Despain, b. 1789, South Carolina d. 10 Sep 1875, Green County, Kentucky (Age 86 years) |
| | 5. Samuel Despain, b. Abt 1794 d. Yes, date unknown |
| | 6. Rebecca Despain, b. Abt 1795, North Carolina d. Yes, date unknown |
| | 7. Nancy Despain, b. Abt 1798 d. Yes, date unknown |
| | 8. Benjamin Despain, b. 25 Jan 1800, Green County, Kentucky d. 27 Feb 1886, Pendleton, Umatilla County, Oregon (Age 86 years) |
| | 9. Susannah Despain, b. 1803 d. Yes, date unknown |
| | 10. Phillip Despain, b. Abt 1805 d. Yes, date unknown |
| | 11. John Despain, b. 16 Nov 1806, Green County, Kentucky d. 14 Jul 1866, Green County, Kentucky (Age 59 years) |
|
Abt 1765 - Yes, date unknown
